Obiettivi formativi
This is an integrated course consisting of two modules, titled General Biology and Histology and Anatomy. It provides essential biological knowledge for understanding the structure and function of macromolecules, cells, and tissues, with a focus on molecular, genetic, and physiological processes. Students gain the tools to analyze biological systems in both normal and pathological conditions, supporting their ability to engage with biotechnological and biomedical challenges. The General Biology module aims to provide students with a solid foundation in cell biology and genetics. By course end, students will distinguish between prokaryotic and eukaryotic cells, classify major macromolecules, and analyze eukaryotic cell structures and functions. They will understand membrane transport, signal transduction, the cytoskeleton’s role, and cellular compartment integration. Students will grasp genetic information flow, mitochondrial energy metabolism, and key cell cycle phases, applying this to gametogenesis and fertilization. They will apply classical genetics to human heredity, interpret karyotypes, identify chromosomal abnormalities, and evaluate genetic mutation impacts. By the end of the course, students will develop: 1) Applying knowledge and understanding: Students will apply theoretical knowledge to interpret basic data, solve problems in cell biology and genetics, and integrate molecular processes into physiological and biotechnological contexts. 2) Making judgements: Students will develop critical thinking to evaluate structure-function relationships, assess cellular dysfunctions, and interpret genetic variations in health and disease. 3) Communication skills: Students will use appropriate scientific terminology to communicate effectively in academic, research, and professional environments. 4) Learning skills: Students will acquire autonomous learning abilities and methodological tools to deepen their understanding in advanced biomedical and biotechnological studies. The educational objectives of the Histology and Anatomy module are to provide students with a comprehensive understanding of the structural organization of the human body, from the macroscopic to the microscopic level. It emphasizes the topographical relationships between structures and the correlation between anatomical structure and function, which is a core concept of histology. Students will acquire knowledge of the organization of the body’s systems, including: • The morphology, position, and relationships of organs within each system. • The main structural characteristics of organs and their functional significance. By the end of the course, students will develop: 1) Knowledge and Understanding: -Knowledge of the macroscopic and microscopic structures of the human body’s systems, using appropriate biomedical terminology. 2) Application of Knowledge: -The ability to apply this knowledge as a foundation for studying related fields such as physiology, pharmacology, and pathological anatomy. 3) Critical Thinking: -The ability to analyze the structural and functional correlations between various body systems. 4) Communication Skills: -Proficiency in biomedical terminology for effective communication within the scientific community. Students with specific needs are encouraged to request a personal meeting at the beginning of the course in order to plan any compensatory and/or dispensatory measures, based on the learning objectives and their individual requirements. It is also recommended to contact the Student Community Inclusion Office at the following link: https://www.unisi.it/ateneo/lavorare-unisi/accoglienza-disabili-e-serviz....
Programma
Module of General Biology: PART 1: Fundamental properties of living organisms. Prokaryotic and eukaryotic cells. PART 2: Chemical composition of living organisms. Biological macromolecules. PART 3: Structure and functions of cellular organelles. The plasma membrane, receptor concept, and signal transduction. The nucleus and chromatin. Smooth and rough endoplasmic reticulum. Ribosomes. Golgi apparatus. Lysosomes and peroxisomes. Mitochondria and cellular respiration. The cytoskeleton and cellular movement. Microtubules and centrioles, microfilaments, and intermediate filaments. PART 4: From DNA to proteins: basic concepts. PART 5: Mechanisms of cell reproduction and death: the cell cycle and its regulation, mitosis, meiosis, apoptosis, and necrosis. Spermatogenesis, oogenesis, and fertilization. PART 6: Basic principles of genetics and hereditary transmission of traits. Chromosomes and karyotype. Mutations: types, origins, and consequences. MODULE HISTOLOGY AND ANATOMY -HISTOLOGY 1. Introduction to Microscopy: Basics of optical and electron microscopy and techniques for histological sample preparation. 2. Tissues formation and maintenance: stem cells. 3. Epithelial Tissue: Morphological and functional description of epithelial cells and tissues, and classification of epithelia (covering and secretory). 4. Proper Connective Tissue: Cellular components and extracellular matrix. Description of the morphology and function of proper connective tissue. 5. Specialized Connective Tissues: Blood. Adipose tissue. Cartilage and bone tissue. Morphological and functional description of cells and matrix components. 6. Nervous Tissue: Morphology and function of nerve cells and their organization in the central and peripheral nervous systems. 7. Muscle Tissue: Skeletal, cardiac, and smooth muscle. Morphological and functional description of muscle fibers and their organization into muscle tissue. -ANATOMY 8. Anatomical Terminology and Nomenclature: Introduction to general anatomical terms. 9. Integumentary System: Structure and function of the skin and its appendages. 10. Locomotor System: Bone, joint, and muscle systems (osteomuscular system) and their functional interrelations. 11. Cardiovascular System: Structure and function of the heart and blood vessels. 12. Respiratory System: Anatomy and function of the respiratory organs. 13. Digestive System: Morphological and functional characteristics of the digestive organs. 14. Urinary System: Structure and function of the kidneys and urinary tract. 15. Reproductive Systems: Male and female reproductive organs and their functions. 16. Nervous System: Organization and function of the central and peripheral nervous systems.
Non è richiesto nessun prerequisito particolare
The course employs an integrated teaching approach that combines lectures, multimedia resources, guided discussions, and visual models to enhance concept comprehension and critical thinking. Active learning is promoted through group projects, peer-teaching, and problem-solving activities. Digital tools and e-learning platforms provide access to interactive materials, quizzes, and video tutorials, supporting self-paced learning. Individual and group tutoring sessions are also available to offer personalized guidance and reinforce understanding throughout the course.
Modalità d'esame
The final grade is calculated as the weighted average of the marks obtained in each module, rounded to the nearest whole number. For details on the assessment methods of each module, please refer to the specific descriptions.
Testi di riferimento
Refer to the texts listed in each module's syllabus
Codice insegnamento 25616