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Università degli studi di Bologna bioinformatics 2022
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  • Molecular detection is cheaper and more reliable than clinical detection, allowing for early disease identification before symptoms appear.
  • Genomics can help identify specific tumors and tailor treatments based on genetic sequences, reducing side effects by targeting precise diseases.
  • Trastuzumab, an antibody against the HER2 receptor, was a significant discovery in personalized medicine but had to be discontinued due to side effects.
  • Huntington disease is caused by a mutation in the huntingtin gene, leading to complete penetrance and cell proliferation issues.
  • Genomics includes not just DNA sequences but also post-sequence modifications like histone regulation and genetic associations.

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