Lezione 3 - clinical virology and antiviral resistance

Viral pathogenesis involves the virus-host interaction, where viruses are obligated parasites that need host survival for replication but must also maintain transmissibility. Many viral infections are asymptomatic, aiding transmission. Virulence genes and mutations affect a virus's ability to cause disease or spread. Highly virulent strains may be less transmissible, but some can persist long-term or infect animal reservoirs. Identifying these genes is crucial for vaccine development. Respiratory tract infection involves specific (IgA) and non-specific defenses, with aerosols being common transmission routes. Alimentary tract infections require virus r